Comparison of Ozempic, Wegovy, and Mounjaro weight loss injections
If you're considering weight loss injections, you may have come across Ozempic, Wegovy, and Mounjaro. These medications are designed to aid in weight loss by reducing appetite, regulating blood sugar levels, and promoting fat loss. But what’s the difference between them, and which one is best for you?
In this guide, we’ll compare Ozempic (Semaglutide), Wegovy (Semaglutide), and Mounjaro (Tirzepatide) to help you make an informed decision.
City | Temperature °F | Forecast | Humidity |
|---|---|---|---|
Washington, DC | 58 | 63% | |
Philadelphia | 58 | 53% | |
New York | 60 | 43% |
Book weight loss injections
What is Ozempic?
Ozempic (Semaglutide)
✔ Originally designed to treat Type 2 diabetes by helping regulate blood sugar
✔ Contains Semaglutide, which mimics GLP-1 (Glucagon-Like Peptide-1) to suppress appetite
✔ Many patients report significant weight loss (even though it’s not FDA-approved for weight management)
✔ Dosage starts at 0.25mg weekly and increases up to 2mg weekly
Who is Ozempic for?
✔ People with Type 2 diabetes who also want to lose weight
✔ Individuals seeking a lower-cost alternative to Wegovy
✔ Those who can tolerate off-label use for weight loss
What is Wegovy?
Wegovy (Semaglutide)
✔ FDA-approved specifically for weight loss
✔ Contains the same active ingredient (Semaglutide) as Ozempic, but at higher doses
✔ Helps patients lose up to 15% of their body weight in clinical trials
✔ Dosage starts at 0.25mg weekly and increases up to 2.4mg weekly
Who is Wegovy for?
✔ Non-diabetic individuals struggling with obesity (BMI of 30+)
✔ People with a BMI of 27+ with weight-related conditions (e.g., high blood pressure, high cholesterol)
✔ Those looking for an FDA-approved weight loss injection
What is Mounjaro?
Mounjaro (Tirzepatide)
✔ A breakthrough weight loss injection that targets two receptors (GLP-1 & GIP) for enhanced weight loss
✔ FDA-approved for Type 2 diabetes and officially approved for weight loss under the name Zepbound
✔ Clinical trials show up to 20% body weight reduction—more than Ozempic or Wegovy
✔ Dosage starts at 2.5mg weekly and increases up to 15mg weekly
Who is Mounjaro for?
✔ Individuals with Type 2 diabetes who also want to lose weight
✔ Those looking for the most effective weight loss injection available
✔ People who have not responded well to Ozempic or Wegovy
Key differences: Ozempic vs. Wegovy vs. Mounjaro
Active ingredients & mechanism
-
Ozempic & Wegovy: Both contain Semaglutide (GLP-1 agonist), which helps reduce appetite and slow digestion.
-
Mounjaro: Contains Tirzepatide, which acts on both GLP-1 and GIP receptors, providing a stronger metabolic effect.
Effectiveness for weight loss
-
Ozempic: 10-15% body weight reduction (off-label use)
-
Wegovy: 15% body weight reduction (FDA-approved for weight loss)
-
Mounjaro: 20% body weight reduction (most effective option)
FDA approval & primary use
-
Ozempic: Approved for diabetes but often used off-label for weight loss
-
Wegovy: Specifically FDA-approved for weight loss
-
Mounjaro: Originally for diabetes, but now approved for weight loss under the name Zepbound
Cost & availability
-
Ozempic: Generally cheaper than Wegovy and Mounjaro
-
Wegovy: Often more expensive but fully designed for weight loss
-
Mounjaro: Highest price point but most effective for weight loss
Side effects
All three injections can cause nausea, vomiting, bloating, and digestive issues, but Mounjaro has a slightly higher risk of hypoglycemia (low blood sugar) in some patients.
Which weight loss injection is right for you?
Choose Ozempic if...
✔ You have Type 2 diabetes and want to lose weight
✔ You want a cost-effective alternative to Wegovy
✔ You’re okay with using a medication off-label for weight loss
Choose Wegovy if...
✔ You want an FDA-approved weight loss injection
✔ You have a BMI of 30+ (or 27+ with weight-related conditions)
✔ You’re looking for long-term, sustainable weight loss
Choose Mounjaro if...
✔ You want the most effective weight loss injection (up to 20% weight loss)
✔ You have Type 2 diabetes and need an injection for both blood sugar control and weight loss
✔ You haven’t had success with Ozempic or Wegovy
Final thoughts: the best weight loss injection for you
All three weight loss injections—Ozempic, Wegovy, and Mounjaro—are highly effective, but the best choice depends on your health condition, weight loss goals, and budget.
✔ Ozempic is best for diabetics who want weight loss as a secondary benefit
✔ Wegovy is ideal for those looking for an FDA-approved weight loss injection
✔ Mounjaro offers the most powerful results but at a higher cost
Before starting any weight loss injection, consult with a medical professional to determine which treatment is best for you.
Book a consultation today and take the first step toward your weight loss journey!
FAQ's Weight loss injections
Why choose Oakridge Aesthetics
Experienced Senior Nurse Practitioner & Nurse Prescriber
21 years of medical experience. MSc level clinical research and advanced clinical assessment training.
Fully trained in aesthetic medicine
CPD accredited training in multiple areas of medical aesthetics. Evidence-based treatments provided only.
Face to face consult with every treatment
The majority of our treatments are prescription only medications. We offer a detailed consultation to ensure your safety whilst prescribing.
Treatments unique and tailored to your desired look
Bespoke treatment plan tailored to suit your individual facial anatomy and desired outomes.
Full medical aesthetics & administration insurance
We hold fully comprehensive medical aesthetics insurance from a registered medics only insurer.
This is my seventh week taking the weight loss treatment and i'm astonished with my weight loss. I've dropped from 113kg to 96.5kg. To say I am delighted is an understatement. Thank you so much Liz, your advice has been invaluable. Worth every penny.
Shey Davies, December 2024